Prime Minister Boris Johnson has insisted on caution as most legal constraints on social contact are lifted in England.
Restrictions on how many people can meet or attend events have been uplifted, nightclubs reopened at midnight, and table service will not be essential in pubs and restaurants.
Face coverings will be suggested in some spaces but not mandated by law.
Vaccines Minister Nadhim Zahawi stated government experts had recommended that only a few under-18s be vaccinated.
The PM, chancellor and the health secretary are self-isolating, and there are cautions cases of Covid will surge.
Mr Zahawi, in a BBC Radio 4’s Today program, defended the U-turn, which saw the prime minister and chancellor self-isolating, after earlier saying they would participate in a pilot program to take daily tests instead.
Mr Zahawi asserted that Mr Johnson only “considered” joining the pilot scheme, adding: “No one is taking anyone for fools.”
However, with more than 68% of UK adults fully vaccinated, modelling hints hospital admissions, severe illness and deaths from Covid-19 will be at a lower level than in earlier surges.
In a video posted on Twitter on Sunday afternoon, the prime minister mentioned, now was the “right moment” to move to the last stage of England’s roadmap out of lockdown.
“If we don’t do it now we’ve got to ask ourselves, when will we ever do it?” he said, further adding that the virus would have the “advantage of the cold weather” in autumn and winter.
“But we’ve got to do it cautiously. We’ve got to remember that this virus is sadly still out there. Cases are rising, we can see the extreme contagiousness of the Delta variant.”
Labour’s shadow health secretary Jonathan Ashworth mentioned ending legal mask necessities. The suggestion to work from home was “reckless” and cautioned of a “day of chaos” on the transport network as people returned to offices after months away.
“The last thing we want on a day like this is chaos and for the public health measures to be undermined,” he shared with BBC Radio 4’s Today program.
But Nadhim Zahawi defended the reopening, stating 90% of the most vulnerable had been vaccinated. It was correct for people to take “personal and corporate responsibility” over measures such as wearing masks. “We’re doing the right thing to get as close to normal as possible, as quickly as possible,” he shared with BBC Breakfast, saying that the closure of the school term would diminish the spread of the virus.
He also said he had got the recommendation from the Joint Committee on Vaccination and Immunization about inoculating children aged 12 to 17 and would make a statement to Parliament on Monday afternoon.
The committee has suggested giving the vaccine to children with illnesses that make them vulnerable to Covid, children who live with someone vulnerable and those who are close to turning 18, he mentioned.
As restrictions lose in England, businesses such as nightclubs – and significant events – will be motivated to use the NHS Covid Pass to check people are fully vaccinated, have natural immunity from infection or have an off late negative test.